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Egg Based Virus Production

Vibalogics offers egg based virus production using Specific Pathogen Free (SPF) or production eggs for both veterinary and human applications.

Our eggs are always sourced from accredited suppliers and all batches are accompanied by the relevant certificates to support use in a GMP environment. The maximum batch size for AAF fluid harvest is 5,000 eggs and the maximum batch size for chicken embryonic fibroblast (CEF) preparations is 1,000 eggs. CEF cultivation can be performed in various systems including roller bottles, CellSTACK or using iCELLis fixed-bed bioreactor technology. Down-stream operations are established and include filtration-based techniques (dead-end, cross-flow and sterile) and ultra-centrifugation.

Vibalogics has experience in egg based virus production, working with the following viruses:

  • Newcastle Disease Virus (NDV, Paramyxoviridae) on both SPF eggs and cell culture for human (cancer therapy) and veterinary (vaccination) applications.
  • Infectious Bursal Disease Virus (IBDV-Gumboro; Birnaviridae)
  • Infectious Bronchitis Virus (IBV; Coronaviridae)
  • Reovirus (Reoviridae)
  • Avian Influenza (Orthomyxoviridae)
  • Egg Drop Syndrome virus (avian Adenovirus)
  • Marek virus (Herpesviridae)
  • Infectious Laryngotracheitis Virus (ILT; Herpesviridae)
  • Avian Encephalomyelitis Virus (AEV; Picornaviridae)
  • Chicken Anaemia Virus (CAV; Circoviridae)
  • Avian Poxvirus (Poxviridae).

With a purpose built facility and expert staff, Vibalogics is a logical choice for egg based virus production at clinical scale.
 
For more information regarding Virus Manufacturing, contact us today on +49 4721 565 400 or email contact@vibalogics.com

Egg Based Virus

Egg based virus production…

…using Specific Pathogen Free (SPF) or production eggs