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We have an established history in SPF egg-based manufacturing, working with the following viruses:

  • Newcastle Disease Virus (NDV, Paramyxoviridae) harvested from AAF; human (cancer therapy) and veterinary (vaccination) applications
  • MVA (on CEF cultures in roller bottles)
  • Infectious Bursal Disease Virus (IBDV-Gumboro; Birnaviridae)
  • Infectious Bronchitis Virus (IBV; Coronaviridae)
  • Reovirus (Reoviridae)
  • Avian Influenza (Orthomyxoviridae)
  • Egg Drop Syndrome virus (Avian Adenovirus)
  • Marek virus (Herpesviridae)
  • Infectious Laryngotracheitis Virus (ILT; Herpesviridae)
  • Avian Encephalomyelitis Virus (AEV; Picornaviridae)
  • Chicken Anaemia Virus (CAV; Circoviridae)
  • Avian Poxvirus (Poxviridae)

Our purpose-built facility and expert team make Vibalogics a logical choice for your egg-based virotherapy production.

Our process comprises: 

  • Order, incoming inspection (candling) and overnight incubation in large climate rooms
  • Optimized egg disinfection procedures (without compromising on egg viability or virus infectivity
  • Manual virus inoculation and egg closure
  • Semi-automated de-capping (egg puncher) and harvest of AAF egg-fluid
  • Preparation of CEFs
  • Cultivation of CEFs in roller bottles and CellSTACK®
  • Storage and bioburden testing of egg-fluid
  • Purification of viruses from egg fluid using optional steps like depth, crossflow and sterile-filtration, homogenization, and sonication